PIONEER or OASIS, which one was the higher dose oral
plain water only, about half a glass, then nothing for 30 minutes. i follow it exactly
#oral-glp1 2026-02-25
Wednesday33 messages6 participantstimes are UTC
Highlights from this day
- step_one_sian — PIONEER or OASIS, which one was the higher dose oral plain water only, about half a glass, then nothing for 30 minutes. i follow it exactly 11:55
- oasis_ola — the 30 minutes starts when you swallow it, and i set a timer because i cannot be trusted the oral mg number is bigger because almost none of it gets in, thats the… 12:15
- oasis_ola — does the 30 minutes start from swallowing or from the water 12:19
- food_noise_off — my oral results were inconsistent week to week and i eventually decided it was me, not the tablet one percent is the number people quote and the spread around it is… 14:16
- food_noise_off — plain water only, about half a glass, then nothing for 30 minutes. i follow it exactly 15:48
my weekly log on oral is noisier than my injectable log ever was, same scales same mornings, thats one data point
[edited]anyone switched from injectable to oral and kept the same effect
tea also does not count, in case anyone was hoping
took mine with breakfast once by accident and that week was a write off, for what its worth
[edited]i keep the tablet by the kettle so i take it before i think about food
mine was patchy too
the fasting window is the difference between a dose and a very expensive tablet, ill dig out the number
right so OASIS ran under the same sort of fasting conditions, thats not the variable between the two
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the 30 minutes starts when you swallow it, and i set a timer because i cannot be trusted
the oral mg number is bigger because almost none of it gets in, thats the entire reason
took 3 weeks before i saw anything on oral, roughly twice what the injection took me
does the 30 minutes start from swallowing or from the water
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unrelated but went back to injecting because the morning routine was too fragile around shift work
big mg small dose
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does SNAC do anything other than get it through the stomach
technique probably
switched from injectable to oral, lost some of the effect, switched back after 19 months
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the oral mg number is bigger because almost none of it gets in, thats the entire reason
changed my mind on the plain water rule after reading how SNAC works, its not a formality
SNAC raises the local pH and protects it long enough to cross, thats its whole job, not advice obviously
is there any point splitting an oral dose
SNAC does the work
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oral was easier on my gut than injecting at what felt like a similar effect, which surprised me
set a timer
my oral results were inconsistent week to week and i eventually decided it was me, not the tablet
one percent is the number people quote and the spread around it is the actual story
*VendorInvestigate not the other one
the inconsistency is mostly technique and admitting that took me about a year
the non peptide orals are the interesting part of this channel now, not oral semaglutide, thats one data point
about one percent
the non peptide agents dose daily without the water ritual, thats the practical difference
back after 7 months, has anything changed on the oral side
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plain water only, about half a glass, then nothing for 30 minutes. i follow it exactly
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PIONEER not OASIS