thirty minutes, no cheating
[edited]#oral-glp1 2026-02-08
Sunday33 messages8 participantstimes are UTC
Highlights from this day
- two_eight_c — did anyone get consistent results on the oral or is it always patchy 17:18
- mid_week_mo — did anyone go back to injecting after trying oral 17:38
- dana_titrates — my weekly log on oral is noisier than my injectable log ever was, same scales same mornings 18:35
- two_eight_c — roughly one percent gets absorbed, which is why the tablet strength looks nothing like an injectable dose, thats just me 18:39
- mid_week_mo — switched from injectable to oral, lost some of the effect, switched back after 8 months 19:01
orforglipron is a small molecule rather than a peptide, which is why the fasting conditions differ
sorry to jump in the non peptide agents dose daily without the water ritual, thats the practical difference
absorption is the variable, not the molecule. same tablet, different morning, different result
plain water only
why is the oral dose in mg so much bigger than the injectable one
is orforglipron a peptide at all
PIONEER or OASIS, which one was the higher dose oral
did anyone get consistent results on the oral or is it always patchy
💀6
quick one i was wrong about the water amount, i was using a sip and it needs a lot more than that
ok so tea also does not count, in case anyone was hoping
the 30 minutes starts when you swallow it, and i set a timer because i cannot be trusted
the inconsistency is mostly technique and admitting that took me about a year
went back to injecting
did anyone go back to injecting after trying oral
⚠️15👍4📈8
how long before the oral did anything measurable for you
*VendorInvestigate not the other one
the fasting window is the difference between a dose and a very expensive tablet, thats just me
follow up the oral mg number is bigger because almost none of it gets in, thats the entire reason
my oral results were inconsistent week to week and i eventually decided it was me, not the tablet
why does the same tablet do different things week to week
slightly off topic but did anyone find the oral easier on the gut than the injection
my weekly log on oral is noisier than my injectable log ever was, same scales same mornings
🧪4
is there any point splitting an oral dose
roughly one percent gets absorbed, which is why the tablet strength looks nothing like an injectable dose, thats just me
SNAC raises the local pH and protects it long enough to cross, thats its whole job
i use it because needles are a genuine problem for me, not because i think its better
the fasting rule cost me my breakfast routine and thats the real reason people quit the oral
switched from injectable to oral, lost some of the effect, switched back after 8 months
👍4
*Janoshik not the other one
does the 30 minutes start from swallowing or from the water
mine was patchy too