i use it because needles are a genuine problem for me, not because i think its better
#oral-glp1 2025-11-19
Wednesday37 messages8 participantstimes are UTC
Highlights from this day
- sharps_comedy — for the archive does the 30 minutes start from swallowing or from the water 11:05
- vienna_vial — does SNAC do anything other than get it through the stomach 13:32
- ferrous_ash — unrelated but how strict is the 30 minute wait before food for people here lost 9kg over 20 months on oral, slower than my injectable stretch, i stuck with it anyway 14:46
went back to injecting
one percent is the number people quote and the spread around it is the actual story
my oral results were inconsistent week to week and i eventually decided it was me, not the tablet
for the archive does the 30 minutes start from swallowing or from the water
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i said 18 months ago that my oral results were random, they got consistent once i fixed the water
OASIS ran under the same sort of fasting conditions, thats not the variable between the two, happy to be corrected
i do 6am with water and eat at 7, thats been my routine for 1 months
ok so does taking it with any food at all just waste the dose
whats the bioavailability actually like, i keep seeing about one percent
absorption is the variable, not the molecule. same tablet, different morning, different result
switched from injectable to oral, lost some of the effect, switched back after 24 months, someone check my working
the 30 minutes starts when you swallow it, and i set a timer because i cannot be trusted
thirty minutes, no cheating
roughly one percent gets absorbed, which is why the tablet strength looks nothing like an injectable dose, for what its worth
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plain water only, about half a glass, then nothing for 30 minutes. i follow it exactly
SNAC does the work
Purity check: no report on file for lot F-1330. Nothing logged either way.
fasted every morning
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coffee doesnt count
Reminder set. I will post here in 7 days.
does SNAC do anything other than get it through the stomach
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nobody should copy my morning routine, but the timer is the bit i would keep
anyone tracking whether their oral results line up week to week
how much water exactly, is it a small sip or half a glass
ruined my breakfast
PIONEER was the original oral semaglutide programme and OASIS looked at the higher oral doses
technique probably
i keep the tablet by the kettle so i take it before i think about food
*VendorInvestigate not the other one
is the plain water rule actually load bearing or is it a formality
big mg small dose
quick one the inconsistency is mostly technique and admitting that took me about a year
coffee is not plain water. i tried it for a month and my results got worse
is orforglipron a peptide at all
unrelated but how strict is the 30 minute wait before food for people here
lost 9kg over 20 months on oral, slower than my injectable stretch, i stuck with it anyway
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i was wrong about the water amount, i was using a sip and it needs a lot more than that, thats one data point