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#oral-glp1 2025-08-13

Wednesday13 messages5 participantstimes are UTC
Highlights from this day
  • pbs_pip — the inconsistency is mostly technique and admitting that took me about a year 18:59
  • ferritin_fay — PIONEER was the original oral semaglutide programme and OASIS looked at the higher oral doses, i could be wrong 19:02
  • question_queue — the non peptide agents dose daily without the water ritual, thats the practical difference, n of 1 obviously the non peptide agents dose daily without the water… 19:54
  • seoul_swirl — is the inconsistency people report about the drug or about how they take it 20:05
  • seoul_swirl — how much water exactly, is it a small sip or half a glass 20:07
PP

tea also does not count, in case anyone was hoping

FF

update on the earlier thing is the absorption variability why the oral doses look so high

PP

the inconsistency is mostly technique and admitting that took me about a year

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FF

PIONEER was the original oral semaglutide programme and OASIS looked at the higher oral doses, i could be wrong

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PP

absorption is the variable, not the molecule. same tablet, different morning, different result, anyway

PP

the 30 minutes starts when you swallow it, and i set a timer because i cannot be trusted, thats just me

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QQ

the non peptide agents dose daily without the water ritual, thats the practical difference, n of 1 obviously
the non peptide agents dose daily without the water ritual, thats the practical difference

FT

oral was easier on my gut than injecting at what felt like a similar effect, which surprised me

does taking it with any food at all just waste the dose

how much water exactly, is it a small sip or half a glass

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update on the earlier thing the oral mg number is bigger because almost none of it gets in, thats the entire reason