vialroom

#oral-glp1 2025-07-01

Tuesday27 messages7 participantstimes are UTC
Highlights from this day
  • chlorhex — went back to injecting because the morning routine was too fragile around shift work 12:54
  • dexa_or_bia — nobody should copy my morning routine, but the timer is the bit i would keep 14:04
  • VialBot — Archive lookup: still_here_2024 first appears in this channel on 2025-04-16. 14:27
  • chlorhex — while im here i said 3 months ago that my oral results were random, they got consistent once i fixed the water, happy to be corrected 15:21
  • chlorhex — does coffee count as plain water, asking for obvious reasons 15:43
TT

the oral disappointed me on the mornings i couldnt manage 30 minutes fasted, which was most of them

CH

switched from injectable to oral, lost some of the effect, switched back after 25 months
splitting a dose made the absorption problem worse rather than better in my own log

TT

whats the bioavailability actually like, i keep seeing about one percent
took mine with breakfast once by accident and that week was a write off

CH

i keep the tablet by the kettle so i take it before i think about food
orforglipron is a small molecule rather than a peptide, which is why the fasting conditions differ

CH

went back to injecting because the morning routine was too fragile around shift work

📈17💀3⚠️13

nobody should copy my morning routine, but the timer is the bit i would keep

💀10
VB

Archive lookup: still_here_2024 first appears in this channel on 2025-04-16.

🔥6
GG

absorption is the variable, not the molecule. same tablet, different morning, different result

CH

while im here i said 3 months ago that my oral results were random, they got consistent once i fixed the water, happy to be corrected

8👍1
TF

follow up changed my mind on the plain water rule after reading how SNAC works, its not a formality

anyone tracking whether their oral results line up week to week

TF

ok so my oral results were inconsistent week to week and i eventually decided it was me, not the tablet

SH

plain water only, about half a glass, then nothing for 30 minutes. i follow it exactly

DO

the 30 minutes starts when you swallow it, and i set a timer because i cannot be trusted, ill dig out the number

[edited]