vialroom

#oral-glp1 2025-05-16

Friday15 messages4 participantstimes are UTC
Highlights from this day
  • warsaw_vial — for the archive absorption is the variable, not the molecule. same tablet, different morning, different result 01:52
  • shame_and_meds — the fasting rule cost me my breakfast routine and thats the real reason people quit the oral, your mileage will differ 02:32
  • two_four_ceiling — the oral disappointed me on the mornings i couldnt manage 30 minutes fasted, which was most of them 02:34
  • shame_and_meds — update on the earlier thing the 30 minutes starts when you swallow it, and i set a timer because i cannot be trusted 03:22
WV

for the archive absorption is the variable, not the molecule. same tablet, different morning, different result

Cited study
Oral Semaglutide 50 mg in Adults with Overweight or Obesity (OASIS 1)
The Lancet · 2023
The high-dose oral. Absorption rules matter enormously here.

is the plain water rule actually load bearing or is it a formality

mine was patchy too

SA

the fasting window is the difference between a dose and a very expensive tablet, thats just me

[edited]
SA

the fasting rule cost me my breakfast routine and thats the real reason people quit the oral, your mileage will differ

TF

the oral disappointed me on the mornings i couldnt manage 30 minutes fasted, which was most of them

how long before the oral did anything measurable for you

update on the earlier thing the 30 minutes starts when you swallow it, and i set a timer because i cannot be trusted

💀113

plain water only