vialroom

#oral-glp1 2025-04-07

Monday23 messages7 participantstimes are UTC
Highlights from this day
  • retention_time — i take mine at 6am, is 30 minutes really enough 16:33
  • thirty_one_g — slightly off topic but the fasting rule cost me my breakfast routine and thats the real reason people quit the oral, your mileage will differ i said 22 months ago… 18:18
  • cold_chain_cmdr — did OASIS use the same fasting conditions as the earlier work 18:29
LM

splitting a dose made the absorption problem worse rather than better in my own log

for the archive does the 30 minutes start from swallowing or from the water

how strict is the 30 minute wait before food for people here

is the inconsistency people report about the drug or about how they take it

VB

Digest for the week of 2024-11-29 has been published.

not a peptide

SNAC does the work

PIONEER or OASIS, which one was the higher dose oral

TO

slightly off topic but the fasting rule cost me my breakfast routine and thats the real reason people quit the oral, your mileage will differ
i said 22 months ago that my oral results were random, they got consistent once i fixed the water

🔥10🙏11
TO

ok so the inconsistency is mostly technique and admitting that took me about a year

CC

did OASIS use the same fasting conditions as the earlier work

Cited study
Oral Semaglutide 50 mg in Adults with Overweight or Obesity (OASIS 1)
The Lancet · 2023
The high-dose oral. Absorption rules matter enormously here.

SNAC raises the local pH and protects it long enough to cross, thats its whole job

CC

OASIS ran under the same sort of fasting conditions, thats not the variable between the two