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#oral-glp1 2025-03-31

Monday24 messages5 participantstimes are UTC
Highlights from this day
  • eighteen_months — PIONEER was the original oral semaglutide programme and OASIS looked at the higher oral doses the fasting rule cost me my breakfast routine and thats the real reason… 10:56
  • yyz_vial — the oral disappointed me on the mornings i couldnt manage 30 minutes fasted, which was most of them 12:08
  • cold_pack_carla — unrelated but the 30 minutes starts when you swallow it, and i set a timer because i cannot be trusted, your mileage will differ 12:10
  • nordic_price_nils — the fasting window is the difference between a dose and a very expensive tablet changed my mind on the plain water rule after reading how SNAC works, its not a… 12:20
  • nordic_price_nils — OASIS ran under the same sort of fasting conditions, thats not the variable between the two, your mileage will differ 14:19
AB

the non peptide orals are the interesting part of this channel now, not oral semaglutide

[edited]

unrelated but the non peptide agents dose daily without the water ritual, thats the practical difference

plain water only, about half a glass, then nothing for 30 minutes. i follow it exactly

mine was patchy too

1
YV

how much water exactly, is it a small sip or half a glass

EM

PIONEER was the original oral semaglutide programme and OASIS looked at the higher oral doses
the fasting rule cost me my breakfast routine and thats the real reason people quit the oral

YV

my weekly log on oral is noisier than my injectable log ever was, same scales same mornings, i think

YV

lost 18kg over 14 months on oral, slower than my injectable stretch, i stuck with it anyway

the oral disappointed me on the mornings i couldnt manage 30 minutes fasted, which was most of them

🔥18😂9
CP

unrelated but the 30 minutes starts when you swallow it, and i set a timer because i cannot be trusted, your mileage will differ

🤝3
NP

the fasting window is the difference between a dose and a very expensive tablet
changed my mind on the plain water rule after reading how SNAC works, its not a formality

CP

while im here i use it because needles are a genuine problem for me, not because i think its better

NP

OASIS ran under the same sort of fasting conditions, thats not the variable between the two, your mileage will differ

EM

oral was easier on my gut than injecting at what felt like a similar effect, which surprised me

NP

took 25 weeks before i saw anything on oral, roughly twice what the injection took me, ill dig out the number

nobody should copy my morning routine, but the timer is the bit i would keep

EM

i was wrong about the water amount, i was using a sip and it needs a lot more than that