vialroom

#oral-glp1 2025-01-22

Wednesday18 messages5 participantstimes are UTC
Highlights from this day
  • two_lifts_a_week — absorption is the variable, not the molecule. same tablet, different morning, different result 19:54
  • split_dose_sam — does the 30 minutes start from swallowing or from the water 20:39
  • split_dose_sam — ok so how strict is the 30 minute wait before food for people here 20:40
  • triple_ag_tom — anyone dosing oral because of a needle problem rather than preference 20:41
  • triple_ag_tom — does taking it with any food at all just waste the dose 21:53
TL

i do 6am with water and eat at 7, thats been my routine for 12 months, happy to be corrected

absorption is the variable, not the molecule. same tablet, different morning, different result

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RW

the non peptide agents dose daily without the water ritual, thats the practical difference

i keep the tablet by the kettle so i take it before i think about food

mine was patchy too

SD

does the 30 minutes start from swallowing or from the water

Cited study
Oral Semaglutide 50 mg in Adults with Overweight or Obesity (OASIS 1)
The Lancet · 2023
The high-dose oral. Absorption rules matter enormously here.

ok so how strict is the 30 minute wait before food for people here

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TA

anyone dosing oral because of a needle problem rather than preference

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changed my mind on the plain water rule after reading how SNAC works, its not a formality, still working it out

[edited]

technique probably

coffee doesnt count

RW

splitting a dose made the absorption problem worse rather than better in my own log

TA

does taking it with any food at all just waste the dose

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