SURMOUNT-OSA is the stopping one. weight came back on for most people once the drug stopped. that is the finding, not an opinion
#maintenance 2026-01-04
Sunday51 messages12 participantstimes are UTC
Highlights from this day
- impersonator_ip — the maintenance conversation barely existed in here two years ago and now it is half the channel protein went up during maintenance for me rather than down, which was… 14:23
- melb_meniscus — is this forever or is that just how it feels at month 8 16:35
- apob_over_ldl — appetite came back over about three weeks after i reduced, not all at once, which is what i had braced for, happy to be corrected 16:41
- appetite_back — a 10mg vial at a 2mg maintenance dose is five weeks of doses, so my monthly cost roughly halved 17:19
did anyone regret dropping the dose too fast
there is no official maintenance dose. it is a thing we do because the alternative on the table was stopping, ill dig out the number
holidays at maintenance are fine, i take the dose on the day and stop thinking about it
i lift twice a week specifically because losing fast without it cost me more than i was willing to lose
janoshik-d-0718.pdf
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no data on that
how much regain did people get in the first 19 months after stopping
i tried to come down and could not hold it, went back to treatment dose, and stopped apologising for it
Reminder for wren_weighs_in: dose day is today. Set 5 days ago.
coming back to this lower frequency maintenance is genuinely unstudied. anybody telling you it is proven is making that up
lift twice a week
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did your maintenance dose end up higher or lower than you expected it to
coming back after 6 months of maintenance, is anyone interested in the numbers
[edited]harder than losing
regain is expected
does anyone lift specifically to hold onto muscle now that theyre maintaining
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how do you decide youre actually at maintenance rather than just stalled
the maintenance conversation barely existed in here two years ago and now it is half the channel
protein went up during maintenance for me rather than down, which was completely counterintuitive
m0 118.4
m1 113.9
m2 110.2
m3 108.8
m4 108.1 <- the stall
m5 105.0
m6 101.6
m7 99.2come down slower than that
if i go back up after regain does it work the same the second time
how do people handle a two week holiday at a maintenance dose
wren_weighs_inholidays at maintenance are fine, i take the dose on the day and stop thinking about it
is a maintenance dose a real clinical thing or something we invented between us
i weigh weekly at maintenance rather than daily and my range is about two kilos either side
set a trigger weight
food noise coming back at a lower dose settled again after about four weeks for me
follow up dropping to a maintenance dose was uneventful for me and completely miserable for somebody i talk to weekly
no official dose
ok so i stayed at treatment dose for four months past goal and then came down slowly. that order was right for me
the muscle question is the one i wish i had taken seriously at month two instead of month twelve, not advice obviously
nobody here can tell you whether to stop. we can tell you what happened to us when we did
whats a realistic amount of regain to accept rather than panic about
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weekly not daily
Reminder for pia_plateaus: dose day is today. Set 8 days ago.
does anyone budget for maintenance being cheaper or is it the same €38 a month
went back up, no regrets
everybody i have seen stop and hold it did something else as well, without exception in my time here
maintenance is harder than losing because there is no number going down to keep you interested
mine held
anyone tried every ten days or every fortnight as a maintenance schedule
is this forever or is that just how it feels at month 8
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thats fluctuation
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i came off for four months, put 67 back on, and came back. no drama in it, just numbers
i think about it the way i think about my blood pressure tablet, and that framing helped me more than anything else, ymmv
appetite came back over about three weeks after i reduced, not all at once, which is what i had braced for, happy to be corrected
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ok so anyone gone off entirely and stayed off successfully
a 10mg vial at a 2mg maintenance dose is five weeks of doses, so my monthly cost roughly halved
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im holding at 1 for maintenance and wondering whether i should be lower
how long did people stay at treatment dose after hitting goal
regain after stopping is the expected outcome, which is a horrible sentence and also what the data says
two or three kilos up and down is normal fluctuation. ten is a different conversation
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i put 20 back on after stopping and then went back on it. it worked the same the second time round