vialroom

#dosing-titration 2026-06-13

Saturday29 messages10 participantstimes are UTC
Highlights from this day
  • tenpence — i hold for two months minimum before i decide a dose has stopped doing anything 12:59
  • VialBot — Reminder for blind_submit: dose day is today. Set 2 days ago. 13:29
  • redefine_ren — if i hold at 15 indefinitely am i losing anything 17:21
TE

i hold for two months minimum before i decide a dose has stopped doing anything

weights-monthly.csv
880 rows · not retained in the public archive

came down from a treatment dose to maintenance over about three months and it was uneventful

🙏1
DD

i went to the top of the ladder, felt no better than two rungs down, and came back. that is data for me and nobody else, i think
a missed week does not reset you, but going straight back to the top dose after a gap is how people get floored

SF

if the current dose is still working, going up is spending headroom you might want later

you do not have to escalate at all. that is a real option that gets forgotten

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n of 1

VB

Reminder for blind_submit: dose day is today. Set 2 days ago.

🙏16
TE

nobody here can tell you what dose to be on and the ones who try get corrected

BS

how do you decide between holding and stepping when both feel wrong

BS

plateau versus set point is not answerable in under six months of data

ok so i have been at 12 for 1 months and honestly i have stopped wanting to move

FT

i drifted from sunday to wednesday over a year and only noticed when i checked the log

FT

the trials escalated on a fixed schedule because a trial has to. you are not a trial, n of 1 obviously

whats a sensible maintenance dose after a year at treatment dose

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i log dose, day, weight and one line about how the week felt. thats enough to make decisions on

came down, no regrets

RR

if i hold at 15 indefinitely am i losing anything

⚠️7💀16🔥11

pick a day and stick to it

with a roughly seven day half-life you are near steady state after about five weeks at a dose

a missed week does not reset you, but going straight back to the top dose after a gap is how people get floored

SS

while im here is there a trial anywhere that studied twice weekly, or is it all anecdote