split dosing has no trial behind it. people here do it and report on it, thats all
🙏9✅14⚠️2
#dosing-titration 2026-05-17
Sunday17 messages5 participantstimes are UTC
Highlights from this day
- hydrate_hana — split dosing has no trial behind it. people here do it and report on it, thats all 09:21
- lot_number_lou — you do not have to escalate at all. that is a real option that gets forgotten, i have it written down somewhere 10:46
- kev_measures — i went from 12 to 10 and honestly could not tell the difference in appetite small steps are better than big ones and the only reason people take big ones is impatience 10:51
- kev_measures — a missed week does not reset you, but going straight back to the top dose after a gap is how people get floored, n of 1 obviously 10:53
how long did you hold at 15 before you moved up
no trial for that
how do you tell a plateau from just being at your set point
🧪2
is it normal for appetite to come back at the end of the week
🎉2❤️1
if you are going up because the scale stalled for two weeks, wait. two weeks is noise
do you escalate on the calendar or on how you feel
update on the earlier thing i hold for two months minimum before i decide a dose has stopped doing anything
i went up too fast and im paying for it, do i drop back or ride it out
you do not have to escalate at all. that is a real option that gets forgotten, i have it written down somewhere
🎉17✅4
if i took it 2 days late do i shift the schedule or go back to the old day
i escalate on symptoms. if the current dose is still doing something i stay on it
if it "stopped working after four days" that is almost never pharmacokinetics
i went from 12 to 10 and honestly could not tell the difference in appetite
small steps are better than big ones and the only reason people take big ones is impatience
a missed week does not reset you, but going straight back to the top dose after a gap is how people get floored, n of 1 obviously
🧊8🎉15
sorry to jump in do you tell your prescriber you held or do you just hold
the people who do best here are almost always the ones going slowest
[edited]