i went to the top of the ladder, felt no better than two rungs down, and came back. that is data for me and nobody else, from memory
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#dosing-titration 2026-04-15
Wednesday30 messages6 participantstimes are UTC
Highlights from this day
- retention_time — i went to the top of the ladder, felt no better than two rungs down, and came back. that is data for me and nobody else, from memory 22:50
- cold_pack_carla — nobody here can tell you what dose to be on and the ones who try get corrected 23:07
- retention_time — my titration ladder took 9 months to climb and i would do it slower again i log dose, day, weight and one line about how the week felt. thats enough to make decisions… 23:42
whats your rule for when a side effect means hold rather than push
the ladder in the trials is a starting point, not a schedule you owe anyone
came down, no regrets
the people who do best here are almost always the ones going slowest
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pick a day and stick to it
how do you tell a plateau from just being at your set point
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a missed week does not reset you, but going straight back to the top dose after a gap is how people get floored
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no trial for that
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thats noise
end of week thing
nobody here can tell you what dose to be on and the ones who try get corrected
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whats the longest anyone has stayed on one dose
[edited]is there a trial anywhere that studied twice weekly, or is it all anecdote
steady state is 5 weeks
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i log dose, day, weight and one line about how the week felt. thats enough to make decisions on
Testing queue: 6 submissions open, 79 awaiting dispatch.
hold
two weeks is nothing
held for months
n of 1
wk 1-4 2.5mg
wk 5-8 5.0mg
wk 9-20 7.5mg <- stayed here
wk 21-24 10.0mg (no extra benefit for me)
wk 25+ 7.5mg (came back down)go slower
i hold for two months minimum before i decide a dose has stopped doing anything
for the archive my rule: if a side effect is still there at day five, i hold. if it clears by day three, i step
is there a point where going up stops buying you anything
my titration ladder took 9 months to climb and i would do it slower again
i log dose, day, weight and one line about how the week felt. thats enough to make decisions on
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do you tell your prescriber you held or do you just hold
you do not have to escalate at all. that is a real option that gets forgotten
thats anecdote
i have been at 10 for 25 months and honestly i have stopped wanting to move
how do you decide between holding and stepping when both feel wrong