my titration ladder took 15 months to climb and i would do it slower again
#dosing-titration 2026-02-25
Wednesday31 messages9 participantstimes are UTC
Highlights from this day
do you escalate on the calendar or on how you feel
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go slower
is week 21 too early to be thinking about the next step
if you are asking whether to go up, the fact you are asking usually means not yet
Assay note: CPC lot B-0329 reported at 99% of label content.
has anyone gone up and then straight back down and been glad they tried
plateau versus set point is not answerable in under six months of data
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too early imo
fridge-temps.csv
586 rows · not retained in the public archive
coming down from 2.5 to 1, how bad is the appetite rebound
if it "stopped working after four days" that is almost never pharmacokinetics
plateau versus set point is not answerable in under six months of data
do you tell your prescriber you held or do you just hold
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the ladder in the trials is a starting point, not a schedule you owe anyone
if i hold at 12 indefinitely am i losing anything
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n of 1
appetite returning at the end of the week is extremely common and is not the dose failing
pick a day and stick to it
my dose day has drifted 7 days later over 15 months, does it matter
coming back to this i hold for two months minimum before i decide a dose has stopped doing anything
whats a sensible maintenance dose after a year at treatment dose
i log dose, day, weight and one line about how the week felt. thats enough to make decisions on
i went from 2.4 to 7.5 and honestly could not tell the difference in appetite
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Reminder set. I will post here in 4 days.
came down from a treatment dose to maintenance over about three months and it was uneventful
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a missed week does not reset you, but going straight back to the top dose after a gap is how people get floored, i have it written down somewhere
split dosing has no trial behind it. people here do it and report on it, thats all
you do not have to escalate at all. that is a real option that gets forgotten
how long did you hold at 15 before you moved up
my titration ladder took 7 months to climb and i would do it slower again
right so the trials escalated on a fixed schedule because a trial has to. you are not a trial
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is there a point where going up stops buying you anything
what does the room think about jumping a rung to catch up
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