ok so anyone tracked whether a smaller more frequent dose changed their side effects
#dosing-titration 2026-01-23
Friday14 messages5 participantstimes are UTC
Highlights from this day
- mid_week_mo — you do not have to escalate at all. that is a real option that gets forgotten, someone check my working 22:29
- two_ml_two — i have been at 15 for 11 months and honestly i have stopped wanting to move you do not have to escalate at all. that is a real option that gets forgotten 22:41
- two_ml_two — if you are going up because the scale stalled for two weeks, wait. two weeks is noise appetite returning at the end of the week is extremely common and is not the… 22:56
- two_ml_two — unrelated but with a roughly seven day half-life you are near steady state after about five weeks at a dose 23:11
- noct.titrate — the people who do best here are almost always the ones going slowest 23:32
is there a trial anywhere that studied twice weekly, or is it all anecdote
after a gap of more than about three weeks i restart one rung lower. thats my own rule, not advice
too early imo
half life is a week
*week 31 not week 8
if the current dose is still working, going up is spending headroom you might want later
you do not have to escalate at all. that is a real option that gets forgotten, someone check my working
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i have been at 15 for 11 months and honestly i have stopped wanting to move
you do not have to escalate at all. that is a real option that gets forgotten
if you are going up because the scale stalled for two weeks, wait. two weeks is noise
appetite returning at the end of the week is extremely common and is not the dose failing
unrelated but with a roughly seven day half-life you are near steady state after about five weeks at a dose
whats your rule for when a side effect means hold rather than push
whats a sensible maintenance dose after a year at treatment dose
the people who do best here are almost always the ones going slowest
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