came down, no regrets
medutest-report-a-2418.pdf
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#dosing-titration 2025-10-18
Saturday48 messages10 participantstimes are UTC
Highlights from this day
- taipei_tare — whats the longest anyone has stayed on one dose 19:08
- VialBot — Verification log updated: Homopeptide — evidence added, status unchanged. 19:29
- u100_pat — follow up my dose day has drifted 4 days later over 3 months, does it matter i drifted from sunday to wednesday over a year and only noticed when i checked the log 19:33
- VialBot — Digest for the week of 2025-01-05 has been published. 20:19
hold
U-100 syringe: 1 unit = 0.01 ml
10u = 0.10 ml
25u = 0.25 ml
50u = 0.50 ml
100u = 1.00 ml
mg drawn = ml drawn x mg/mlhas anyone gone up and then straight back down and been glad they tried
too early imo
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if i took it 6 days late do i shift the schedule or go back to the old day
i jumped a rung once to catch up after a supply gap and it was a bad week. would not repeat
does a missed week reset anything or do you just carry on
i would hold
thats noise
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do you count from injection day or from when you actually felt it
no trial for that
the people who do best here are almost always the ones going slowest, from memory
after a gap of more than about three weeks i restart one rung lower. thats my own rule, not advice
the argument for splitting is a flatter curve. the argument against is you have doubled your injections for a guess
end of week thing
half life is a week
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how do you decide between holding and stepping when both feel wrong
thats normal
not advice
if you are asking whether to go up, the fact you are asking usually means not yet
[edited]whats the longest anyone has stayed on one dose
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i went to the top of the ladder, felt no better than two rungs down, and came back. that is data for me and nobody else
stepping back down on purpose is a completely reasonable move and this channel should say so more often
appetite returning at the end of the week is extremely common and is not the dose failing
update on the earlier thing if the current dose is still working, going up is spending headroom you might want later
Verification log updated: Homopeptide — evidence added, status unchanged.
whats your rule for when a side effect means hold rather than push
the ladder in the trials is a starting point, not a schedule you owe anyone, n of 1 obviously
follow up my dose day has drifted 4 days later over 3 months, does it matter
i drifted from sunday to wednesday over a year and only noticed when i checked the log
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is there any actual reason to escalate every 4 weeks other than the trial did it
i escalate on symptoms. if the current dose is still doing something i stay on it, thats one data point
the ladder in the trials is a starting point, not a schedule you owe anyone
quick one how much does the last dose still matter 2 days later
ok so do you tell your prescriber you held or do you just hold
Digest for the week of 2025-01-05 has been published.
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whats a sensible maintenance dose after a year at treatment dose
how do you tell a plateau from just being at your set point
if you are going up because the scale stalled for two weeks, wait. two weeks is noise, i could be wrong
the trials escalated on a fixed schedule because a trial has to. you are not a trial
a missed week does not reset you, but going straight back to the top dose after a gap is how people get floored, i have it written down somewhere
steady state is 5 weeks
coming back to this i drifted from sunday to wednesday over a year and only noticed when i checked the log
the trials escalated on a fixed schedule because a trial has to. you are not a trial
held for months
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is week 4 too early to be thinking about the next step
do you escalate on the calendar or on how you feel
split dosing has no trial behind it. people here do it and report on it, thats all
*PeptideMeter not the other one
n of 1
anyone here split their weekly into two and would they do it again