sorry to jump in whats a sensible maintenance dose after a year at treatment dose
#dosing-titration 2025-10-14
Tuesday13 messages4 participantstimes are UTC
Highlights from this day
- power_cut_pia — is there any actual reason to escalate every 4 weeks other than the trial did it the ladder in the trials is a starting point, not a schedule you owe anyone 20:12
- power_cut_pia — nobody here can tell you what dose to be on and the ones who try get corrected, n of 1 obviously 20:14
- amylin_amy — my rule: if a side effect is still there at day five, i hold. if it clears by day three, i step 20:15
not advice
is there a point where going up stops buying you anything
dose day drift is mostly harmless with a weekly compound, but pick a day and defend it
is there any actual reason to escalate every 4 weeks other than the trial did it
the ladder in the trials is a starting point, not a schedule you owe anyone
nobody here can tell you what dose to be on and the ones who try get corrected, n of 1 obviously
my rule: if a side effect is still there at day five, i hold. if it clears by day three, i step
appetite returning at the end of the week is extremely common and is not the dose failing
*Janoshik not the other one
too early imo
with a roughly seven day half-life you are near steady state after about five weeks at a dose
how much does the last dose still matter 2 days later
do you escalate on the calendar or on how you feel