i escalate on symptoms. if the current dose is still doing something i stay on it, happy to be corrected
#dosing-titration 2025-07-19
Saturday22 messages5 participantstimes are UTC
Highlights from this day
- ferritin_fay — came down from a treatment dose to maintenance over about three months and it was uneventful 14:04
- dublin_dose — i went to the top of the ladder, felt no better than two rungs down, and came back. that is data for me and nobody else 14:07
- factory_direct_fi — i log dose, day, weight and one line about how the week felt. thats enough to make decisions on 14:58
- amsterdam_aliquot — coming back to this you do not have to escalate at all. that is a real option that gets forgotten, ask me again in a month 15:23
- ferritin_fay — i hold for two months minimum before i decide a dose has stopped doing anything, your mileage will differ 16:43
pick a day and stick to it
came down from a treatment dose to maintenance over about three months and it was uneventful
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the argument for splitting is a flatter curve. the argument against is you have doubled your injections for a guess
i went to the top of the ladder, felt no better than two rungs down, and came back. that is data for me and nobody else
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my dose day has drifted 9 days later over 7 months, does it matter
nobody here can tell you what dose to be on and the ones who try get corrected
i drifted from sunday to wednesday over a year and only noticed when i checked the log
the people who do best here are almost always the ones going slowest
the trials escalated on a fixed schedule because a trial has to. you are not a trial, thats just me
my titration ladder took 13 months to climb and i would do it slower again, anyway
i log dose, day, weight and one line about how the week felt. thats enough to make decisions on
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thats anecdote
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coming back to this you do not have to escalate at all. that is a real option that gets forgotten, ask me again in a month
steady state is 5 weeks
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go slower
do you count from injection day or from when you actually felt it
n of 1
held for months
the ladder in the trials is a starting point, not a schedule you owe anyone
i hold for two months minimum before i decide a dose has stopped doing anything, your mileage will differ
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hold