#dosing-titration 2025-06-23

Reminder set. I will post here in 6 days.

held for months

if it "stopped working after four days" that is almost never pharmacokinetics, ask me again in a month

the trials escalated on a fixed schedule because a trial has to. you are not a trial

my titration ladder took 1 months to climb and i would do it slower again, i could be wrong

the ladder in the trials is a starting point, not a schedule you owe anyone, i could be wrong

nobody here can tell you what dose to be on and the ones who try get corrected

for the archive a missed week does not reset you, but going straight back to the top dose after a gap is how people get floored

my dose day has drifted 9 days later over 6 months, does it matter

i drifted from sunday to wednesday over a year and only noticed when i checked the log, ask me again in a month

came down, no regrets

if you are asking whether to go up, the fact you are asking usually means not yet

no trial for that

too early imo

i went from 2 to 7.5 and honestly could not tell the difference in appetite, for what its worth
a missed week does not reset you, but going straight back to the top dose after a gap is how people get floored

my rule: if a side effect is still there at day five, i hold. if it clears by day three, i step, not advice obviously

anyone here split their weekly into two and would they do it again

with a roughly seven day half-life you are near steady state after about five weeks at a dose

half life is a week