is week 26 too early to be thinking about the next step
the people who do best here are almost always the ones going slowest
#dosing-titration 2024-12-17
Tuesday28 messages8 participantstimes are UTC
Highlights from this day
- split_dose_sam — with a roughly seven day half-life you are near steady state after about five weeks at a dose 15:58
- low_and_slow — if it "stopped working after four days" that is almost never pharmacokinetics 17:30
- surpass_two — i drifted from sunday to wednesday over a year and only noticed when i checked the log 19:17
- gradient_greg — do you count from injection day or from when you actually felt it 19:57
i hold for two months minimum before i decide a dose has stopped doing anything
i escalate on symptoms. if the current dose is still doing something i stay on it, your mileage will differ
is it normal for appetite to come back at the end of the week
i would hold
with a roughly seven day half-life you are near steady state after about five weeks at a dose
👀10
i went from 5 to 1 and honestly could not tell the difference in appetite
how much does the last dose still matter 6 days later
16:36tenpence pinned a message to this channel
update question: did anyone who held for 2 months regret it
hold
the honest answer is that most of us are running protocols nobody has ever studied
if it "stopped working after four days" that is almost never pharmacokinetics
⚠️7❤️10
the ladder in the trials is a starting point, not a schedule you owe anyone
my titration ladder took 9 months to climb and i would do it slower again
appetite returning at the end of the week is extremely common and is not the dose failing
does a missed week reset anything or do you just carry on
if i hold at 10 indefinitely am i losing anything
i escalate on symptoms. if the current dose is still doing something i stay on it
my rule: if a side effect is still there at day five, i hold. if it clears by day three, i step, i could be wrong
how long did you hold at 0.25 before you moved up
coming back to this if the current dose is still working, going up is spending headroom you might want later
not advice
i drifted from sunday to wednesday over a year and only noticed when i checked the log
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*Janoshik not the other one
if i took it 5 days late do i shift the schedule or go back to the old day
do you count from injection day or from when you actually felt it
U-100 syringe: 1 unit = 0.01 ml
10u = 0.10 ml
25u = 0.25 ml
50u = 0.50 ml
100u = 1.00 ml
mg drawn = ml drawn x mg/ml🔥6👀18🧊15