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#dosing-titration 2024-12-09

Monday22 messages5 participantstimes are UTC
Highlights from this day
  • brisbane_bac — holding is not failing. most people here who lasted two years held at least one dose for months appetite returning at the end of the week is extremely common and is… 08:48
  • meniscus_mel — the trials escalated on a fixed schedule because a trial has to. you are not a trial 09:33
  • hydrate_hana — split dosing has no trial behind it. people here do it and report on it, thats all, n of 1 obviously 10:04
RT

my rule: if a side effect is still there at day five, i hold. if it clears by day three, i step

thats noise

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RR

after a gap of more than about three weeks i restart one rung lower. thats my own rule, not advice

BB

ok so you do not have to escalate at all. that is a real option that gets forgotten

peptidemeter-summary-d-0718.pdf
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holding is not failing. most people here who lasted two years held at least one dose for months
appetite returning at the end of the week is extremely common and is not the dose failing

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BB

i escalate on symptoms. if the current dose is still doing something i stay on it

how do you tell a plateau from just being at your set point

HH

split dosing has no trial behind it. people here do it and report on it, thats all, n of 1 obviously

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RR

small steps are better than big ones and the only reason people take big ones is impatience

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nobody here can tell you what dose to be on and the ones who try get corrected

HH

is there a trial anywhere that studied twice weekly, or is it all anecdote

for the archive anyone here split their weekly into two and would they do it again

RR

if you are asking whether to go up, the fact you are asking usually means not yet, ask me again in a month

i have been at 2.4 for 24 months and honestly i have stopped wanting to move

RR

update on the earlier thing plateau versus set point is not answerable in under six months of data

came down from a treatment dose to maintenance over about three months and it was uneventful
plateau versus set point is not answerable in under six months of data

coming down from 1.7 to 2, how bad is the appetite rebound