how do you decide between holding and stepping when both feel wrong
#dosing-titration 2024-12-06
Friday10 messages2 participantstimes are UTC
Highlights from this day
- deadspace — is it normal for appetite to come back at the end of the week 16:40
- deadspace — split dosing has no trial behind it. people here do it and report on it, thats all i went from 7.5 to 0.5 and honestly could not tell the difference in appetite 16:43
- deadspace — do you escalate on the calendar or on how you feel 16:45
my titration ladder took 14 months to climb and i would do it slower again
coming back to this i jumped a rung once to catch up after a supply gap and it was a bad week. would not repeat, anyway
is it normal for appetite to come back at the end of the week
fridge-temps.csv
908 rows · not retained in the public archive
split dosing has no trial behind it. people here do it and report on it, thats all
i went from 7.5 to 0.5 and honestly could not tell the difference in appetite
do you escalate on the calendar or on how you feel
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
is there a trial anywhere that studied twice weekly, or is it all anecdote
my titration ladder took 10 months to climb and i would do it slower again
the ladder in the trials is a starting point, not a schedule you owe anyone
no trial for that