whats the smallest step anyone has managed between doses
#dosing-titration 2024-11-18
Monday14 messages4 participantstimes are UTC
Highlights from this day
- electrolyte_eli — update from 19 months ago: held at the same dose the whole time and still losing slowly 19:08
- slow.taper — appetite returning at the end of the week is extremely common and is not the dose failing 19:11
- electrolyte_eli — my rule: if a side effect is still there at day five, i hold. if it clears by day three, i step 19:33
- meniscus_mel — ok so if you are going up because the scale stalled for two weeks, wait. two weeks is noise, happy to be corrected 20:05
thats anecdote
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do you tell your prescriber you held or do you just hold
update from 19 months ago: held at the same dose the whole time and still losing slowly
nobody here can tell you what dose to be on and the ones who try get corrected
appetite returning at the end of the week is extremely common and is not the dose failing
my rule: if a side effect is still there at day five, i hold. if it clears by day three, i step
steady state is 5 weeks
half life is a week
ok so if you are going up because the scale stalled for two weeks, wait. two weeks is noise, happy to be corrected
if you are asking whether to go up, the fact you are asking usually means not yet
i drifted from sunday to wednesday over a year and only noticed when i checked the log
thats noise
i would hold
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
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