Archive lookup: retention_time first appears in this channel on 2024-01-11.
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#dosing-titration 2024-08-25
Sunday17 messages5 participantstimes are UTC
Highlights from this day
- VialBot — Archive lookup: retention_time first appears in this channel on 2024-01-11. 09:30
- u100_pat — i drifted from sunday to wednesday over a year and only noticed when i checked the log 09:47
- u100_pat — after a gap of more than about three weeks i restart one rung lower. thats my own rule, not advice 11:20
steady state is 5 weeks
i went to the top of the ladder, felt no better than two rungs down, and came back. that is data for me and nobody else
i drifted from sunday to wednesday over a year and only noticed when i checked the log
U-100 syringe: 1 unit = 0.01 ml
10u = 0.10 ml
25u = 0.25 ml
50u = 0.50 ml
100u = 1.00 ml
mg drawn = ml drawn x mg/mlhold
go slower
the ladder in the trials is a starting point, not a schedule you owe anyone
if it "stopped working after four days" that is almost never pharmacokinetics
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too early imo
my rule: if a side effect is still there at day five, i hold. if it clears by day three, i step
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the people who do best here are almost always the ones going slowest
i would hold
follow up whats the longest anyone has stayed on one dose
thats anecdote
after a gap of more than about three weeks i restart one rung lower. thats my own rule, not advice
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follow up small steps are better than big ones and the only reason people take big ones is impatience
update from 26 months ago: held at the same dose the whole time and still losing slowly