vialroom

#dosing-titration 2024-08-23

Friday15 messages4 participantstimes are UTC
Highlights from this day
  • vialkeeper — anyone here split their weekly into two and would they do it again 23:22
  • vialkeeper — the argument for splitting is a flatter curve. the argument against is you have doubled your injections for a guess, take that with a pinch of salt 23:26
  • vialkeeper — after a gap of more than about three weeks i restart one rung lower. thats my own rule, not advice 23:32
  • vialkeeper — came down from a treatment dose to maintenance over about three months and it was uneventful 23:48
  • vialkeeper — a missed week does not reset you, but going straight back to the top dose after a gap is how people get floored, thats just me 23:58
LL

i hold for two months minimum before i decide a dose has stopped doing anything

VI

anyone here split their weekly into two and would they do it again

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CO

how do you decide between holding and stepping when both feel wrong

VI

the argument for splitting is a flatter curve. the argument against is you have doubled your injections for a guess, take that with a pinch of salt

❤️8👀1

i escalate on symptoms. if the current dose is still doing something i stay on it

update from 4 months ago: held at the same dose the whole time and still losing slowly

after a gap of more than about three weeks i restart one rung lower. thats my own rule, not advice

3❤️2

end of week thing

[edited]

whats a sensible maintenance dose after a year at treatment dose

CO

ok so dose day drift is mostly harmless with a weekly compound, but pick a day and defend it, happy to be corrected

half life is a week

i went from 0.25 to 15 and honestly could not tell the difference in appetite

NT

if you are going up because the scale stalled for two weeks, wait. two weeks is noise

[edited]
VI

came down from a treatment dose to maintenance over about three months and it was uneventful

🔥7👍1
VI

a missed week does not reset you, but going straight back to the top dose after a gap is how people get floored, thats just me

🧊18