dose day drift is mostly harmless with a weekly compound, but pick a day and defend it
#dosing-titration 2024-08-12
Monday16 messages6 participantstimes are UTC
Highlights from this day
- VialBot — Recon calculator: 40mg in 5ml = 10mg/ml. 17:17
- rotate_the_site — quick one came down from a treatment dose to maintenance over about three months and it was uneventful, happy to be corrected 17:19
- reta_resting_hr — if the current dose is still working, going up is spending headroom you might want later 17:43
- rotate_the_site — ok so small steps are better than big ones and the only reason people take big ones is impatience my titration ladder took 9 months to climb and i would do it slower… 18:10
- reta_resting_hr — if i hold at 12 indefinitely am i losing anything if the current dose is still working, going up is spending headroom you might want later 18:57
i would hold
whats your rule for when a side effect means hold rather than push
end of week thing
update from 21 months ago: held at the same dose the whole time and still losing slowly
Recon calculator: 40mg in 5ml = 10mg/ml.
quick one came down from a treatment dose to maintenance over about three months and it was uneventful, happy to be corrected
📈1
if you are going up because the scale stalled for two weeks, wait. two weeks is noise
two weeks is nothing
if the current dose is still working, going up is spending headroom you might want later
steady state is 5 weeks
reta_resting_hrif the current dose is still working, going up is spending headroom you might want later
anyone here split their weekly into two and would they do it again
ok so small steps are better than big ones and the only reason people take big ones is impatience
my titration ladder took 9 months to climb and i would do it slower again
is there a point where going up stops buying you anything
plateau versus set point is not answerable in under six months of data
if i hold at 12 indefinitely am i losing anything
if the current dose is still working, going up is spending headroom you might want later