i drifted from sunday to wednesday over a year and only noticed when i checked the log
#dosing-titration 2024-07-09
Tuesday32 messages7 participantstimes are UTC
Highlights from this day
- customs_owl — if i hold at 2.4 indefinitely am i losing anything 23:15
- taper_tess — unrelated but i went to the top of the ladder, felt no better than two rungs down, and came back. that is data for me and nobody else, ask me again in a month 23:22
- customs_owl — after a gap of more than about three weeks i restart one rung lower. thats my own rule, not advice 23:29
- noct.titrate — you do not have to escalate at all. that is a real option that gets forgotten 23:33
for the archive what does the room think about jumping a rung to catch up
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plateau versus set point is not answerable in under six months of data
do you count from injection day or from when you actually felt it
the people who do best here are almost always the ones going slowest
if it "stopped working after four days" that is almost never pharmacokinetics
pick a day and stick to it
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with a roughly seven day half-life you are near steady state after about five weeks at a dose, thats just me
i log dose, day, weight and one line about how the week felt. thats enough to make decisions on
if the current dose is still working, going up is spending headroom you might want later, not advice obviously
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coming back to this i went from 7.5 to 5 and honestly could not tell the difference in appetite
my titration ladder took 19 months to climb and i would do it slower again
my dose day has drifted 5 days later over 17 months, does it matter
i went up too fast and im paying for it, do i drop back or ride it out
anyone tracked whether a smaller more frequent dose changed their side effects
*PeptideMeter not the other one
if i hold at 2.4 indefinitely am i losing anything
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
my rule: if a side effect is still there at day five, i hold. if it clears by day three, i step
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do you tell your prescriber you held or do you just hold
unrelated but i went to the top of the ladder, felt no better than two rungs down, and came back. that is data for me and nobody else, ask me again in a month
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stepping back down on purpose is a completely reasonable move and this channel should say so more often, from memory
anyone here split their weekly into two and would they do it again
after a gap of more than about three weeks i restart one rung lower. thats my own rule, not advice
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n of 1
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you do not have to escalate at all. that is a real option that gets forgotten
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split_dose_samcoming back to this i went from 7.5 to 5 and honestly could not tell the difference in…
half life is a week
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two weeks is nothing
if you are going up because the scale stalled for two weeks, wait. two weeks is noise
steady state is 5 weeks
the honest answer is that most of us are running protocols nobody has ever studied
end of week thing