#dosing-titration 2024-06-03

plateau versus set point is not answerable in under six months of data

the honest answer is that most of us are running protocols nobody has ever studied

is week 27 too early to be thinking about the next step

ok so stepping back down on purpose is a completely reasonable move and this channel should say so more often

how much does the last dose still matter 4 days later

you do not have to escalate at all. that is a real option that gets forgotten

my dose day has drifted 5 days later over 26 months, does it matter

half life is a week

while im here i escalate on symptoms. if the current dose is still doing something i stay on it
split dosing has no trial behind it. people here do it and report on it, thats all

go slower

i went to the top of the ladder, felt no better than two rungs down, and came back. that is data for me and nobody else

update question: did anyone who held for 14 months regret it

if you are going up because the scale stalled for two weeks, wait. two weeks is noise

not advice

split dosing has no trial behind it. people here do it and report on it, thats all

genuine question if you are asking whether to go up, the fact you are asking usually means not yet, ymmv

unrelated but with a roughly seven day half-life you are near steady state after about five weeks at a dose

end of week thing

i drifted from sunday to wednesday over a year and only noticed when i checked the log

i would hold

pick a day and stick to it

is there a point where going up stops buying you anything

is there any actual reason to escalate every 4 weeks other than the trial did it