net peptide is gross mass minus water minus counterion. that is why 11.4mg of powder can be a correct 10mg vial
#coa-reading 2026-05-12
Tuesday13 messages3 participantstimes are UTC
Highlights from this day
- mhra_unlicensed — net peptide is gross mass minus water minus counterion. that is why 11.4mg of powder can be a correct 10mg vial 18:49
- mhra_unlicensed — no lot number, no certificate. a document you cannot tie to the vial in your hand is decoration, from memory 19:01
- dog_person_dev — water content is why an honest 10mg vial assays at 9.1. karl fischer titration, and most certificates omit it 19:05
- dog_person_dev — if you only read one line on a certificate, read the lot number. if you read two, read the assay 19:54
- dog_person_dev — nobody can authenticate a certificate from a scan. you authenticate the material by testing it yourself 20:32
is sterility tested as part of a normal purity certificate
an identical chromatogram on two different lots is the single biggest tell there is, we shall see
no lot number, no certificate. a document you cannot tie to the vial in your hand is decoration, from memory
📈7💀10
if the certificate date precedes the lot date, ask. sometimes it is sloppiness and sometimes it is not
water content is why an honest 10mg vial assays at 9.1. karl fischer titration, and most certificates omit it
thats the counterion
if you only read one line on a certificate, read the lot number. if you read two, read the assay
📈9
nobody can authenticate a certificate from a scan. you authenticate the material by testing it yourself
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the three way match is vial, certificate, invoice. if all three agree you have something
one decimal versus two is usually just house style, not precision
coming back to this is area percent the same thing as how many mg are in the vial
i have never seen a research certificate with an endotoxin result on it. not once