a vial can be 99.4% pure and hold 8.1mg of a 10mg label. both numbers are true and only one of them is the one you care about
#coa-reading 2026-03-26
Thursday12 messages4 participantstimes are UTC
Highlights from this day
- willow_waits — nobody can authenticate a certificate from a scan. you authenticate the material by testing it yourself 18:36
- underfill_uma — ok so whats the related substances table actually telling me 19:01
- acetate_ash — net peptide is gross mass minus water minus counterion. that is why 11.4mg of powder can be a correct 10mg vial 19:57
- acetate_ash — a lab that reports "greater than 98%" rather than a number is telling you they did not integrate carefully 20:40
- evidence_or_not — an identical chromatogram on two different lots is the single biggest tell there is 21:19
is endotoxin ever tested on research material
nobody can authenticate a certificate from a scan. you authenticate the material by testing it yourself
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ok so whats the related substances table actually telling me
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sloppy not sinister
peak RRT area% note
1 0.42 0.31 solvent front
2 0.88 0.44 related substance
3 1.00 98.72 main
4 1.14 0.53 related substanceif the certificate date precedes the lot date, ask. sometimes it is sloppiness and sometimes it is not
*Janoshik not the other one
net peptide is gross mass minus water minus counterion. that is why 11.4mg of powder can be a correct 10mg vial
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a lab that reports "greater than 98%" rather than a number is telling you they did not integrate carefully
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gross mass on a jewellery scale plus the water content is enough to catch most underfills
an identical chromatogram on two different lots is the single biggest tell there is
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tfa counterion runs higher by mass than acetate. if the certificate does not say, you cannot do the mass balance