does anyone keep a folder of certificates to compare over time
📈4
#coa-reading 2025-02-03
Monday13 messages4 participantstimes are UTC
Highlights from this day
- net_peptide — does anyone keep a folder of certificates to compare over time 18:37
- ferrous_ash — a supplier certificate on its own is a starting point, not evidence. that is the whole reason the verification channel exists, your mileage will differ 20:55
- ten_of_ten — single wavelength detection can miss a co-eluting impurity that does not absorb there, not advice obviously 20:57
- net_peptide — sterility and endotoxin are separate tests and almost nobody runs either on research material, anyway i was wrong about this for a year: area percent under-reports… 22:27
two certificates from the same supplier have an identical chromatogram, is that normal
a certificate should name the method, the instrument, the column and the operator. most name none of those
good certificate actually
looks re-dated
how do you verify a certificate is actually from the lab it says
whats the minimum a certificate has to have before you take it seriously
sloppy not sinister
residual solvents matter more than people think for anything that went through a lot of purification steps
a supplier certificate on its own is a starting point, not evidence. that is the whole reason the verification channel exists, your mileage will differ
👀7😂5
single wavelength detection can miss a co-eluting impurity that does not absorb there, not advice obviously
🧪3
sterility and endotoxin are separate tests and almost nobody runs either on research material, anyway
i was wrong about this for a year: area percent under-reports nothing, it just answers a different question than assay does
purity is not assay