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Thread · #cagrilintide · 2025-08-09

i was sceptical about monotherapy and after 15 months

Spun off from a message in #cagrilintide on 2025-08-09. 17 messages, 5 participants.

The message this came from
  • quiet.hours — i was sceptical about monotherapy and after 15 months im still sceptical, just less so 17:21
SS

its an amylin analogue, different receptor family, so treating it as another GLP-1 is the first mistake

MM

the nausea felt different rather than less, more fullness and less of the queasy wave

🎉4
SS

the fullness thing is the part people describe differently, food stops being interesting rather than repellent

📈11
AB

the fullness effect hasnt faded over 15 months, unlike my semaglutide appetite curve

MM

REDEFINE is the phase 3 programme, most of what gets quoted casually in here is earlier work

RR

the fullness thing is the part people describe differently, food stops being interesting rather than repellent