#cagrilintide 2026-04-08

Wednesday19 messages6 participantstimes are UTC

Highlights from this day

tb500_tobias — dropped the GLP-1 and stayed on this alone for 5 months, appetite held but weight barely moved 23:10
tb500_tobias — while im here the reason nausea reads differently is timing, mine arrived on the second day rather than the first, i think 23:15
tb500_tobias — two Janoshik results on the same Homopeptide lot came back 96.8 and 99, closer than i expected 23:20
blank_run — i said earlier this year that monotherapy did nothing for me, and at a higher dose it did something 23:25
alt_ast_ali — the combination is the thing with trial data behind it, monotherapy in here is mostly us guessing 23:36

does amylin do something about fullness that the GLP-1 doesnt

noticed something around week 34 on monotherapy, well after i had given up expecting to

CagriSema is cagrilintide with semaglutide and REDEFINE is the trial programme around it

anyone stopped the GLP-1 and kept only this

weekly for me, same day every week, no reason beyond habit

does the fullness effect fade the way appetite suppression does

monotherapy was underwhelming for me and i say that as someone who wanted it to work

is anyone running this on its own or is it all CagriSema in here

fullness rather than nausea

dropped the GLP-1 and stayed on this alone for 5 months, appetite held but weight barely moved

while im here the reason nausea reads differently is timing, mine arrived on the second day rather than the first, i think

two Janoshik results on the same Homopeptide lot came back 96.8 and 99, closer than i expected

i said earlier this year that monotherapy did nothing for me, and at a higher dose it did something

did anyone find monotherapy underwhelming

underwhelming honestly

how slow are people titrating this compared to retatrutide

the combination is the thing with trial data behind it, monotherapy in here is mostly us guessing

is the weekly schedule the same here

titrating dead slow