unrelated but £72 for a 15 vial and it lasts me longer than the GLP-1 does at my doses
#cagrilintide 2026-03-21
Saturday37 messages7 participantstimes are UTC
Highlights from this day
- two_three_lifts — anyone got two VendorInvestigate results on the same HJ lot for this 09:14
- two_three_lifts — coming back to this the fullness thing is the part people describe differently, food stops being interesting rather than repellent, happy to be corrected 09:42
- sharps_bin_sid — whats the recon people use, 40 in 2.5ml 13:32
- mcg_not_mg — amylin analogue, so its not a GLP-1 at all right 16:32
- tarpit_tam — anyone holding at 1.7 for a while before stepping 16:50
anyone got two VendorInvestigate results on the same HJ lot for this
you cannot tell which of the two is doing what in a combination and i stopped pretending i could
is the nausea profile genuinely different or am i imagining it
the numbers everyone quotes come from the combination, so comparing them to monotherapy logs is unfair, i have it written down somewhere
coming back to this the fullness thing is the part people describe differently, food stops being interesting rather than repellent, happy to be corrected
📉1💀5
different not less
🙏18👍3🎉1
anyone dosing this on a different day to their cagrilintide
titrating dead slow
cant separate them
📈2💀1
stopped for 8 months and the fullness went within a fortnight of the last dose
did anyone find monotherapy underwhelming
held mine a while
📉2📈10
monotherapy question, did appetite move for you without a GLP-1 alongside
fullness rather than nausea
separate days
does amylin do something about fullness that the GLP-1 doesnt
the slower titration in here is community habit as much as anything, the trials had their own schedule
whats the recon people use, 40 in 2.5ml
👀1📉13
has REDEFINE reported or are people quoting earlier work
CagriSema is cagrilintide with semaglutide and REDEFINE is the trial programme around it
nobody should copy my schedule, im describing it because people asked what a slow ramp looks like
amylin not glp-1
did the nausea feel different to you or just less
slower than the others
👀3
lost 66lb over 14 months on the combination and i genuinely cannot apportion it
cagrisema thats it
for the archive the fullness effect hasnt faded over 18 months, unlike my semaglutide appetite curve
*Janoshik not the other one
combination for me
thats the phase 3 one
amylin analogue, so its not a GLP-1 at all right
⚠️1📈2🧊7
REDEFINE is the trial
anyone holding at 1.7 for a while before stepping
⚠️1👀4📉15
40 in 0.5ml gives 2mg/ml which is what i use, purely because the units come out round
held at 1 for 4 months on monotherapy before i touched it again
is the combination just the two dosed together or a single formulation