weekly for me, same day every week, no reason beyond habit
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#cagrilintide 2026-02-17
Tuesday13 messages4 participantstimes are UTC
Highlights from this day
- mcg_not_mg — weekly for me, same day every week, no reason beyond habit 22:34
- charge_state — i said earlier this year that monotherapy did nothing for me, and at a higher dose it did something, from memory 22:57
- two_three_lifts — you cannot tell which of the two is doing what in a combination and i stopped pretending i could 23:03
- charge_state — follow up the numbers everyone quotes come from the combination, so comparing them to monotherapy logs is unfair 23:24
the fullness thing is the part people describe differently, food stops being interesting rather than repellent
back after 14 months, is monotherapy still a minority thing here
REDEFINE is the phase 3 programme, most of what gets quoted casually in here is earlier work
REDEFINE is the trial
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i said earlier this year that monotherapy did nothing for me, and at a higher dose it did something, from memory
40 in 2ml gives 2.5mg/ml which is what i use, purely because the units come out round
you cannot tell which of the two is doing what in a combination and i stopped pretending i could
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different not less
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does amylin do something about fullness that the GLP-1 doesnt
follow up the numbers everyone quotes come from the combination, so comparing them to monotherapy logs is unfair
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CagriSema is cagrilintide with semaglutide and REDEFINE is the trial programme around it
slightly off topic but is the nausea profile genuinely different or am i imagining it