titrating dead slow
#cagrilintide 2025-09-21
Sunday26 messages8 participantstimes are UTC
Highlights from this day
- half_life_hal — unrelated but did the combination change your GI compared to the GLP-1 alone 14:08
- half_life_hal — nobody should copy my schedule, im describing it because people asked what a slow ramp looks like 15:06
- VialBot — Reminder for half_life_hal: dose day is today. Set 9 days ago. 15:28
- orfor_watch — two Medutest results on the same CPC lot came back 97.4 and 98.6, closer than i expected 17:31
CagriSema is cagrilintide with semaglutide and REDEFINE is the trial programme around it, ymmv
unrelated but did the combination change your GI compared to the GLP-1 alone
coa-h-2814.pdf
1 page · 802 KB · not retained in the public archive
the fullness effect hasnt faded over 7 months, unlike my semaglutide appetite curve
is the slower titration because of nausea or something else
did anyone find monotherapy underwhelming
*PeptideMeter not the other one
5 in 3ml gives 10mg/ml which is what i use, purely because the units come out round
fullness rather than nausea
nobody should copy my schedule, im describing it because people asked what a slow ramp looks like
⚠️1🎉9🧊18
changed my mind on this, i started thinking amylin was the interesting bit and now i think its the pairing
the combination is the thing with trial data behind it, monotherapy in here is mostly us guessing
is there a reason people titrate this over more weeks than the others
whats the recon people use, 20 in 2.5ml
right so lost 30lb over 5 months on the combination and i genuinely cannot apportion it
Reminder for half_life_hal: dose day is today. Set 9 days ago.
cant separate them
ok so combination GI was worse than either alone for me, which is not what i had read anywhere
half_life_halnobody should copy my schedule, im describing it because people asked what a slow ramp…
does amylin do something about fullness that the GLP-1 doesnt
how many weeks before you noticed anything on monotherapy
amylin not glp-1
coa-b-0329.pdf
1 page · 708 KB · not retained in the public archive
unrelated but whats REDEFINE testing exactly
back after 23 months, is monotherapy still a minority thing here
i keep the two on separate days so if something goes wrong i have a chance of knowing which
two Medutest results on the same CPC lot came back 97.4 and 98.6, closer than i expected
cagrisema thats it