amylin not glp-1
#cagrilintide 2025-09-16
Tuesday21 messages3 participantstimes are UTC
Highlights from this day
- plateau_pen — dosing them on different days made no difference i could detect 13:41
- eight_mm — weekly for me, same day every week, no reason beyond habit, still working it out 14:37
- eight_mm — the combination is the thing with trial data behind it, monotherapy in here is mostly us guessing 14:58
- eight_mm — for the archive whats REDEFINE testing exactly 15:01
dosing them on different days made no difference i could detect
[edited]🙏9
i keep the two on separate days so if something goes wrong i have a chance of knowing which
combination for me
went slower because the first step gave me two rough days and i took that as information
5 in 0.5ml gives 5mg/ml which is what i use, purely because the units come out round
😂4🧊4
amylin is about slowed gastric emptying and satiety signalling, thats the short version and im no pharmacologist
the slower titration in here is community habit as much as anything, the trials had their own schedule, not advice obviously
weekly for me, same day every week, no reason beyond habit, still working it out
monotherapy was underwhelming for me and i say that as someone who wanted it to work
monotherapy here
the reason nausea reads differently is timing, mine arrived on the second day rather than the first
the combination is the thing with trial data behind it, monotherapy in here is mostly us guessing
😂4✅17🤝6
stopped for 24 months and the fullness went within a fortnight of the last dose, ask me again in a month
for the archive whats REDEFINE testing exactly
🔥17⚠️2📉6
update on the earlier thing i was sceptical about monotherapy and after 10 months im still sceptical, just less so
[edited]cant separate them
cagrisema thats it
if youre used to GLP-1 titration steps this feels absurdly cautious and i still do it that way
dropped the GLP-1 and stayed on this alone for 7 months, appetite held but weight barely moved
slower than the others
💀16❤️4