slower than the others
[edited]#cagrilintide 2025-08-01
Friday16 messages4 participantstimes are UTC
Highlights from this day
- evidence_or_not — amylin is about slowed gastric emptying and satiety signalling, thats the short version and im no pharmacologist 22:00
- lead_time_lars — does amylin do something about fullness that the GLP-1 doesnt 22:31
- lead_time_lars — the combination is the thing with trial data behind it, monotherapy in here is mostly us guessing 22:34
- appetite_back — if youre used to GLP-1 titration steps this feels absurdly cautious and i still do it that way 22:37
is the combination just the two dosed together or a single formulation
amylin is about slowed gastric emptying and satiety signalling, thats the short version and im no pharmacologist
held at 2 for 2 months on monotherapy before i touched it again
the nausea felt different rather than less, more fullness and less of the queasy wave
dosing them on different days made no difference i could detect
REDEFINE is the trial
🧪2📈5
is anyone running this on its own or is it all CagriSema in here
monotherapy did work for me, just slower and smaller than i expected
thats the phase 3 one
*PeptideMeter not the other one
does amylin do something about fullness that the GLP-1 doesnt
😂1
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the combination is the thing with trial data behind it, monotherapy in here is mostly us guessing
is the slower titration because of nausea or something else
if youre used to GLP-1 titration steps this feels absurdly cautious and i still do it that way