#cagrilintide 2025-07-25

lost 74lb over 8 months on the combination and i genuinely cannot apportion it

does the fullness effect fade the way appetite suppression does

amylin not glp-1

combination GI was worse than either alone for me, which is not what i had read anywhere, still working it out

Reminder set. I will post here in 3 days.

follow up did anyone add this to an existing semaglutide dose rather than starting both

is the slower titration because of nausea or something else

titrating dead slow

£120 for a 5 vial and it lasts me longer than the GLP-1 does at my doses

cagrisema thats it

the numbers everyone quotes come from the combination, so comparing them to monotherapy logs is unfair

*Janoshik not the other one

how slow are people titrating this compared to tirzepatide

i was sceptical about monotherapy and after 19 months im still sceptical, just less so

fullness rather than nausea

is there a reason people titrate this over more weeks than the others
went slower because the first step gave me two rough days and i took that as information

monotherapy here

right so did the nausea feel different to you or just less

if youre used to GLP-1 titration steps this feels absurdly cautious and i still do it that way, ask me again in a month

unrelated but is the combination just the two dosed together or a single formulation

is the nausea profile genuinely different or am i imagining it
the fullness effect hasnt faded over 12 months, unlike my semaglutide appetite curve

genuine question dropped the GLP-1 and stayed on this alone for 5 months, appetite held but weight barely moved, happy to be corrected

thats the phase 3 one