monotherapy question, did appetite move for you without a GLP-1 alongside
#cagrilintide 2025-07-01
Tuesday28 messages7 participantstimes are UTC
Highlights from this day
- tare_weight — genuine question the slower titration in here is community habit as much as anything, the trials had their own schedule 19:45
- VialBot — New independent result logged — Homopeptide, lot D-0718, purity 99.2% (Janoshik). 19:48
- tare_weight — did anyone add this to an existing semaglutide dose rather than starting both 20:00
- private_script_pri — anyone got two Janoshik results on the same GGPeps lot for this 20:42
quick one amylin analogue, so its not a GLP-1 at all right
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changed my mind on this, i started thinking amylin was the interesting bit and now i think its the pairing
[edited]has REDEFINE reported or are people quoting earlier work
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is the nausea profile genuinely different or am i imagining it
held at 10 for 5 months on monotherapy before i touched it again
genuine question the slower titration in here is community habit as much as anything, the trials had their own schedule
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New independent result logged — Homopeptide, lot D-0718, purity 99.2% (Janoshik).
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did anyone add this to an existing semaglutide dose rather than starting both
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held mine a while
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cant separate them
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monotherapy here
thats the phase 3 one
anyone stopped the GLP-1 and kept only this
how do people separate which of the two is doing what in a combination
anyone got two Janoshik results on the same GGPeps lot for this
back after 3 months, is monotherapy still a minority thing here
is the weekly schedule the same here
titrating dead slow
right so CagriSema is cagrilintide with semaglutide and REDEFINE is the trial programme around it
fullness rather than nausea
combination for me
for the archive dosing them on different days made no difference i could detect, ill dig out the number
cagrisema thats it
did the combination change your GI compared to the GLP-1 alone
the fullness effect hasnt faded over 4 months, unlike my semaglutide appetite curve
went slower because the first step gave me two rough days and i took that as information
does the fullness effect fade the way appetite suppression does