amylin is about slowed gastric emptying and satiety signalling, thats the short version and im no pharmacologist
#cagrilintide 2025-04-25
Friday26 messages7 participantstimes are UTC
Highlights from this day
- cold_chain_cmdr — genuine question stopped for 3 months and the fullness went within a fortnight of the last dose 09:33
- seizure_letter — the combination is the thing with trial data behind it, monotherapy in here is mostly us guessing 10:43
- still_here_2024 — i keep the two on separate days so if something goes wrong i have a chance of knowing which 11:55
update on the earlier thing does amylin do something about fullness that the GLP-1 doesnt
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whats REDEFINE testing exactly
cant separate them
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is the weekly schedule the same here
*PeptideMeter not the other one
titrating dead slow
genuine question stopped for 3 months and the fullness went within a fortnight of the last dose
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did the nausea feel different to you or just less
whats the recon people use, 30 in 1ml
combination GI was worse than either alone for me, which is not what i had read anywhere
lost 26lb over 10 months on the combination and i genuinely cannot apportion it
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sorry to jump in is anyone running this on its own or is it all CagriSema in here
the combination is the thing with trial data behind it, monotherapy in here is mostly us guessing
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unrelated but went slower because the first step gave me two rough days and i took that as information
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you cannot tell which of the two is doing what in a combination and i stopped pretending i could
anyone holding at 7.5 for a while before stepping
monotherapy was underwhelming for me and i say that as someone who wanted it to work, i could be wrong
two Medutest results on the same TFC lot came back 99 and 99.2, closer than i expected, we shall see
40 in 2ml gives 2mg/ml which is what i use, purely because the units come out round
cagrisema thats it
coming back to this dosing them on different days made no difference i could detect
did anyone add this to an existing tirzepatide dose rather than starting both
thats the phase 3 one
i keep the two on separate days so if something goes wrong i have a chance of knowing which
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monotherapy here