#cagrilintide 2025-04-11

how do people separate which of the two is doing what in a combination

went slower because the first step gave me two rough days and i took that as information
if youre used to GLP-1 titration steps this feels absurdly cautious and i still do it that way

noticed something around week 25 on monotherapy, well after i had given up expecting to

combination for me

did the combination change your GI compared to the GLP-1 alone

its an amylin analogue, different receptor family, so treating it as another GLP-1 is the first mistake

is the nausea profile genuinely different or am i imagining it

i titrated over twice as many weeks as i did on semaglutide and that was right for me

the slower titration in here is community habit as much as anything, the trials had their own schedule, i have it written down somewhere
the combination is the thing with trial data behind it, monotherapy in here is mostly us guessing

i was sceptical about monotherapy and after 1 months im still sceptical, just less so

combination GI was worse than either alone for me, which is not what i had read anywhere, n of 1 obviously

right so if youre used to GLP-1 titration steps this feels absurdly cautious and i still do it that way

did anyone find monotherapy underwhelming

separate days

dosing them on different days made no difference i could detect

5 in 1ml gives 10mg/ml which is what i use, purely because the units come out round