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#cagrilintide 2025-02-04

Tuesday27 messages7 participantstimes are UTC
Highlights from this day
  • amber_vial — anyone got two Medutest results on the same HJ lot for this 21:49
  • ten_of_ten — whats REDEFINE testing exactly 22:15
  • batch_bandit — 30 in 0.5ml gives 4mg/ml which is what i use, purely because the units come out round, from memory 22:35
  • batch_bandit — two Janoshik results on the same HJ lot came back 97.4 and 99, closer than i expected 22:44

the fullness thing is the part people describe differently, food stops being interesting rather than repellent

noticed something around week 18 on monotherapy, well after i had given up expecting to

AV

does amylin do something about fullness that the GLP-1 doesnt

SA

right so monotherapy question, did appetite move for you without a GLP-1 alongside

TO

went slower because the first step gave me two rough days and i took that as information

GB

weekly for me, same day every week, no reason beyond habit
amylin is about slowed gastric emptying and satiety signalling, thats the short version and im no pharmacologist

is the slower titration because of nausea or something else

BB

30 in 0.5ml gives 4mg/ml which is what i use, purely because the units come out round, from memory

👍18📉5

unrelated but nobody should copy my schedule, im describing it because people asked what a slow ramp looks like

BB

two Janoshik results on the same HJ lot came back 97.4 and 99, closer than i expected

FF

does the fullness effect fade the way appetite suppression does

📉1❤️1
TO

follow up stopped for 24 months and the fullness went within a fortnight of the last dose, i could be wrong

fullness rather than nausea

you cannot tell which of the two is doing what in a combination and i stopped pretending i could

is anyone running this on its own or is it all CagriSema in here

CagriSema is cagrilintide with semaglutide and REDEFINE is the trial programme around it

anyone holding at 7.5 for a while before stepping