vialroom

#cagrilintide 2025-01-16

Thursday20 messages5 participantstimes are UTC
Highlights from this day
  • acetate_ash — is the weekly schedule the same here 15:05
  • pbs_pip — dropped the GLP-1 and stayed on this alone for 10 months, appetite held but weight barely moved 16:31
  • VialBot — New independent result logged — QSC, lot B-0114, purity 98.1% (Medutest). 16:41
  • week_zero — noticed something around week 20 on monotherapy, well after i had given up expecting to lost 95lb over 3 months on the combination and i genuinely cannot apportion it 17:33
  • week_zero — two VendorInvestigate results on the same HJ lot came back 98.6 and 98.1, closer than i expected 17:58
AA

its an amylin analogue, different receptor family, so treating it as another GLP-1 is the first mistake

the nausea felt different rather than less, more fullness and less of the queasy wave

PP

dropped the GLP-1 and stayed on this alone for 10 months, appetite held but weight barely moved

2❤️11📉4

you cannot tell which of the two is doing what in a combination and i stopped pretending i could

REDEFINE is the trial

held at 1 for 4 months on monotherapy before i touched it again

VB

New independent result logged — QSC, lot B-0114, purity 98.1% (Medutest).

🎉18📈10
WZ

did the combination change your GI compared to the GLP-1 alone

nobody should copy my schedule, im describing it because people asked what a slow ramp looks like

lost 18lb over 20 months on the combination and i genuinely cannot apportion it

amylin analogue, so its not a GLP-1 at all right

slower than the others

VL

the numbers everyone quotes come from the combination, so comparing them to monotherapy logs is unfair

WZ

two VendorInvestigate results on the same HJ lot came back 98.6 and 98.1, closer than i expected