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#cagrilintide 2024-11-08

Friday23 messages5 participantstimes are UTC
Highlights from this day
  • cold_chain_cmdr — if youre used to GLP-1 titration steps this feels absurdly cautious and i still do it that way, thats one data point i keep the two on separate days so if something… 10:27
  • vacuum_vic — back after 17 months, is monotherapy still a minority thing here 12:00
  • vacuum_vic — did anyone find monotherapy underwhelming 13:35
CC

if youre used to GLP-1 titration steps this feels absurdly cautious and i still do it that way, thats one data point
i keep the two on separate days so if something goes wrong i have a chance of knowing which

right so anyone stopped the GLP-1 and kept only this

AA

the numbers everyone quotes come from the combination, so comparing them to monotherapy logs is unfair

CC

its an amylin analogue, different receptor family, so treating it as another GLP-1 is the first mistake

VV

lost 10lb over 12 months on the combination and i genuinely cannot apportion it, not advice obviously

AA

quick one noticed something around week 2 on monotherapy, well after i had given up expecting to, thats one data point

SL

the fullness effect hasnt faded over 1 months, unlike my semaglutide appetite curve, for what its worth

VV

back after 17 months, is monotherapy still a minority thing here

📉16🙏9
NP

combination GI was worse than either alone for me, which is not what i had read anywhere

NP

nobody should copy my schedule, im describing it because people asked what a slow ramp looks like

REDEFINE is the trial

fullness rather than nausea

amylin not glp-1

[edited]
NP

you cannot tell which of the two is doing what in a combination and i stopped pretending i could

i keep the two on separate days so if something goes wrong i have a chance of knowing which

$38 for a 30 vial and it lasts me longer than the GLP-1 does at my doses